PPTA | Immunoglobulin Literature Database
| The effects of immune globulin on endotoxemia. |
The effects of immune globulin on endotoxemia. Endo S, Inada K, Yamada Y, Takakuwa T, Nakae H, Kasai T, Kikuchi M, Terashima M, Hoshi S, Yoshida M. Iwate Medical University, Morioka, Japan. Ten patients (mean age, 40 years; 2 women) with endotoxemia received 2.5 gm of immune globulin daily for 4 days or 5 gm daily for 2 days. In all patients, plasma endotoxin levels decreased to normal levels (< or = 9.8 pg/ml) within a mean of 3.2 days after starting immune globulin treatment, and body temperatures decreased to < 37 degrees C within 4.5 days. In 10 antibiotic-treated (control) patients with endotoxemia who did not receive immune globulin, plasma endotoxin levels declined to normal levels in 6 and their body temperatures dropped to normal levels within 5.0 days; no changes in body temperature were noted in the 4 patients whose plasma endotoxin levels did not decrease. PMID: 1286485 [PubMed - indexed for MEDLINE] |
