Literature database

[Toxic epidermal necrolysis. Therapy in ICU with intravenous immunoglobulins in a case]
 Rev Med Chil. 2000 Dec;128(12):1343-8.

[Toxic epidermal necrolysis. Therapy in ICU with intravenous immunoglobulins in a case]

[Article in Spanish]

Andresen M, Boghero Y, Molgo M, Dougnao A, Diaz O.

Programa de Medicina Intensiva, Intensivo Medico, Hospital Clinico de la Universidad Catolica, Departamentos de Medicina Interna y Dermatologia, Facultad de Medicina Pontificia Universidad Catolica de Chile, Santiago de Chile.

We report a 27 years old homosexual male with AIDS that was admitted to the ICU dehydrated, with fever and severe malaise. He had irregular bullae, an extensive purpuric exanthema and a zone of epidermic detachment in the right arm. A toxic epidermal necrolysis was diagnosed and therapy with i.v. immunoglobulins was started. After four days of treatment, bullous lesions disappeared and the extension of exanthema decreased. Toxic epidermal necrolysis is a potentially fatal disease and the use of intravenous immunoglobulins for this condition has been reported as successful.

Publication Types:
  • Case Reports

PMID: 11227243 [PubMed - indexed for MEDLINE]