PPTA | Immunoglobulin Literature Database
| Cardiac troponin I in fulminant adenovirus myocarditis treated with a 24-hour infusion of high-dose |
Cardiac troponin I in fulminant adenovirus myocarditis treated with a 24-hour infusion of high-dose intravenous immunoglobulin. Briassoulis G, Papadopoulos G, Zavras N, Pailopoulos V, Hatzis T, Thanopoulos V. Pediatric Intensive Care Unit, Aghia Sophia Children's Hospital, Levadias & Thivon Street, Athens, Greece. We report a successful outcome on an acute adenovirus myocarditis treated with a 24-hour high-dose intravenous immunoglobulin (24-HDIVIG) in a 4.5-year-old girl. A postviral etiology of acute myocarditis was assessed on the basis of the polymerase chain reaction technique. Among other early markers of cardiac injury, cardiac isoform of troponin-I (cTnI) was significantly correlated to the left ventricular ejection fraction (r = -0.86, p < 0.0001). Follow-up of cTnI, which might also be correlated to the short-term outcome, allows fast, easy, and noninvasive estimation of response to the aggressive treatment with 24-HDIVIG in acute adenovirus myocarditis in children. Publication Types:
PMID: 10865023 [PubMed - indexed for MEDLINE]
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